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It was discovered that naltrexone and bupropion combined, which can be marketed down the road as Contrave, have better weight loss results than exercise and dieting alone.

Using two separate drugs to shed pounds can be very effective you can find combinations while watching FDA now awaiting approval. When dealing with weight loss and the people who go through it you should err along the side of caution and let the FDA do its job and demand some study be done in order that the public knows the side effects and hazards of the medications before we drive them. Keep in mind that drug companies have been in business to make money and that they would say almost anything to keep people on the medications.

Researchers discovered that participants taking this drug for any year, lost excess weight within 4 weeks and have kept the weight off throughout the 56 weeks from the study. Contrave is often a combination in the drugs naltrexone and bupropion, which generally seems to reflect a whole new trend of weight-loss drugs which might be made up of many active ingredient, which might make them more efficient and safer.

Combo-pilling will be the newest fad or better yet the newest ahead under scrutiny and for that reason it is just more publicly known although in the past, comb-pilling to lose weight has been around since the eighties. The biggest reason that using a combination of pills is becoming popular may be the fact that by right now there are no long term prescription weight loss supplements that have been approved by the FDA other than orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications and some of the combinations have been rejected or have yet to be licensed by the FDA.

Seizures certainly are a side effect with Contrave and shouldn't be taken in people who have seizure disorders. The drug can also raise hypertension and heartrate, and must not be used in those with a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy with all the drug.

The FDA also warned that Contrave can raise hypertension and heartrate and must not be used in patients with uncontrolled high hypertension, along with by anyone with heart-related and cerebrovascular (circulation dysfunction impacting the mind) disease. Patients using a history of cardiac arrest or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes using a boxed warning to alert medical researchers and patients for the increased probability of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for smoking cessation.

"There were no warning signs of depression or suicidal thoughts in trial participants," said Fujioka.